Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
8.3 mcg (333 IU)
42%
Calcium (elemental) (from 1,270 mg Calcium Citrate)
266 mg
20%
Magnesium (elemental) (from 230 mg Magnesium Oxide)
133 mg
32%
Vitamin K2 (as Menaquinone)
30 mcg
†
Top Medical Research Studies
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
7
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More
Most Useful Reviews
9
Better well-being
Sound sleep and healthy teeth! The ingredients are good quality. The complex includes calcium for bones and magnesium. The neutral taste and sturdy packaging make this beneficial for improving well-being. It effectively replenishes deficiencies.
Read More
9
Helpful sleep aid
Excellent! This calcium and magnesium formula supports bone health and aids sleep.
Read More
9
Immune boost
Calcium perfectly strengthened my immune system, while magnesium ensured I had healthy sleep. I recommend it to everyone; you will not regret it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
- All Researches
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More
7
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
Read More
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Better well-being
Sound sleep and healthy teeth! The ingredients are good quality. The complex includes calcium for bones and magnesium. The neutral taste and sturdy packaging make this beneficial for improving well-being. It effectively replenishes deficiencies.
Read More
9
Helpful sleep aid
Excellent! This calcium and magnesium formula supports bone health and aids sleep.
Read More
9
Immune boost
Calcium perfectly strengthened my immune system, while magnesium ensured I had healthy sleep. I recommend it to everyone; you will not regret it.
Read More
7.5
Nighttime remedy
Late night assistance! I struggled with sleep issues until a friend suggested calcium/magnesium. I tried the Now brand, which works wonders. I sleep much better after taking calcium with dinner each evening.
Read More
7.5
Improved sleep quality
Cheap price; calcium and magnesium at night can enhance sleep.
Read More
Frequently Asked Questions
7.5
Nighttime remedy
Late night assistance! I struggled with sleep issues until a friend suggested calcium/magnesium. I tried the Now brand, which works wonders. I sleep much better after taking calcium with dinner each evening.
9
Immune boost
Calcium perfectly strengthened my immune system, while magnesium ensured I had healthy sleep. I recommend it to everyone; you will not regret it.
9
Helpful sleep aid
Excellent! This calcium and magnesium formula supports bone health and aids sleep.
7.5
Improved sleep quality
Cheap price; calcium and magnesium at night can enhance sleep.
9
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.
Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
4
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.
Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.
This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
References
- Kilavuz A, Celikhisar H, Dasdemir Ilkhan G. The Association of Serum 25(OH) Vitamin D Level with Severity of Obstructive Sleep Apnea Syndrome in Patients with Syndrome Z (the Interaction of Obstructive Sleep Apnea with Metabolic Syndrome). Metab Syndr Relat Disord. 2021;19:549. 10.1089/met.2021.0066
- Ayyıldız F, Yıldıran H, Afandiyeva N, Gülbahar Ö, Köktürk O. The effects of vitamin D supplemantation on prognosis in patients with mild obstructive sleep apnea syndrome. Turk J Med Sci. 2021;51:2524. 10.3906/sag-2101-83
- Kerley CP, Hutchinson K, Bramham J, McGowan A, Faul J, et al. Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study. J Clin Sleep Med. 2017;13:19. 10.5664/jcsm.6378
- Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. 10.1016/j.jad.2024.05.002
